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Dr. Andrew Rynne

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Does Delayed Period With Nausea And Increased Appetite A Sign Of Pregnancy?

I just got off the Mirena on the 21st of last month, August, had a period about 5 days after for about 5 days. I have not had my next period yet, and have symtoms of nausea, increased apetite, emotional, and tired! I just had a pregnancy test that is negative that says it does not rule out early pregnancy! I am worried and getting tired of waiting to test and to know what is going on with my body! Am I pregnant or is it side effects of taking te Mirena out!
Fri, 6 May 2016
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OBGYN 's  Response
Hallow Dear,

I would have appreciated had you mentioned for how many days your periods have been delayed.

Since you are off Mirena, your contraceptive protection has been removed and you do stand chances of pregnancy. However, we never diagnose the pregnancy only on symptoms; it should be confirmed by pregnancy test and/or clinical examination.

The report of pregnancy test 'pregnancy cannot be rules out' is rather ambiguous. Does it mean that the pregnancy test is week? If so, the possible causes are :

1. Test is performed too early. Probably a repeat test after 4 days might confirm the diagnosis of pregnancy.

2. Ectopic pregnancy : In this condition the pregnancy is implanted somewhere outside the uterine cavity - most commonly tube. Such pregnancy cannot grow and there is always a risk of rupture of the tube. This is bleeding emergency requiring many units of blood transfusion and surgical intervention.

I would suggest you to opt for ultrasonography. If the uterine cavity is empty in spite of the (?weak) positive pregnancy test, the chances of ectopic pregnancy have to be considered strongly. Laparoscopy may help in confirming the diagnosis and also offering conservative management to save the tube.

If ectopic pregnancy is diagnosed before the rupture of the tube, it can be managed conservatively by either Methotrexate or by Microsurgery through Laparoscopy.

My advice to you is not to wait for few more days for the pregnancy test to become positive. Please get Ectopic pregnancy ruled out first.

Better to err on safer side!

If it is not ectopic pregnancy and turns out to be an intrauterine pregnancy, you can manage it safely. If it is an unwanted pregnancy and you want to terminate it, there are medicines available with Gynaecologist's advise to terminate it.

So, please do not waste time; report to your Gynaecologist ASAP.

Dr. Nishikant Shrotri
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OBGYN Dr. Nishikant Shrotri's  Response
Hallow Dear,

The first cardinal sign of pregnancy is missing a period, which you have not. Moreover, your pregnancy test is negative. So you would not be pregnant. They mention 'Negative test does not rule out pregnancy' because if performed very early, it may report false negative results; otherwise these are very reliable tests.

Mirena is an intrauterine device which is Levonorgestrel-releasing intrauterine device. Levonorgestrel is a Progesterone preparation. It is known to cause some side effects like nausea, breast tenderness, lethargy, etc. Since this progesterone is a slow release one, even after removal of Mirena, these effects will remain for few days.

I do not feel you are pregnant. All your symptoms are due to effects of Levonorgestrel. Tab. Pantoprazole may give you some relief.

Still if you want to have confirmation about your pregnancy status, you may go for Beta hCG test. Levels below 5 indicate no pregnancy while if pregnant, they will be more than 25.

I hope this will help you.

Dr. Nishikant Shrotri
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Does Delayed Period With Nausea And Increased Appetite A Sign Of Pregnancy?

Hallow Dear, I would have appreciated had you mentioned for how many days your periods have been delayed. Since you are off Mirena, your contraceptive protection has been removed and you do stand chances of pregnancy. However, we never diagnose the pregnancy only on symptoms; it should be confirmed by pregnancy test and/or clinical examination. The report of pregnancy test pregnancy cannot be rules out is rather ambiguous. Does it mean that the pregnancy test is week? If so, the possible causes are : 1. Test is performed too early. Probably a repeat test after 4 days might confirm the diagnosis of pregnancy. 2. Ectopic pregnancy : In this condition the pregnancy is implanted somewhere outside the uterine cavity - most commonly tube. Such pregnancy cannot grow and there is always a risk of rupture of the tube. This is bleeding emergency requiring many units of blood transfusion and surgical intervention. I would suggest you to opt for ultrasonography. If the uterine cavity is empty in spite of the (?weak) positive pregnancy test, the chances of ectopic pregnancy have to be considered strongly. Laparoscopy may help in confirming the diagnosis and also offering conservative management to save the tube. If ectopic pregnancy is diagnosed before the rupture of the tube, it can be managed conservatively by either Methotrexate or by Microsurgery through Laparoscopy. My advice to you is not to wait for few more days for the pregnancy test to become positive. Please get Ectopic pregnancy ruled out first. Better to err on safer side! If it is not ectopic pregnancy and turns out to be an intrauterine pregnancy, you can manage it safely. If it is an unwanted pregnancy and you want to terminate it, there are medicines available with Gynaecologist s advise to terminate it. So, please do not waste time; report to your Gynaecologist ASAP. Dr. Nishikant Shrotri