HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
159 Doctors Online

By proceeding, I accept the Terms and Conditions

Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

HCM Blog Instant Access to Doctors
HCM BlogQuestions Answered
HCM Blog Satisfaction

Does Increasing The Dosage Of Melatonin Max To 180 Mg Dangerous?

MY HUSBAND HAS LATE STAGE PROSTATE CANCER WHICH RESPONDED VERY WELL TO IPT (INSULIN THERAPY) HIS PSA DROPPED FROM 379 TO 96. CANCER CELLS IN BLOOD DROPPED FROM 51 TO 0. UNFORTUNATELY EVEN SMALL AMOUNTS OF CHEMO. ARE PLAYING HAVOC WITH HIS RED BLOOD CELLS, HIS WHITE CELLS AND HIS HEMOGLOBIN IS ABOUT 8.6? A DR. HAS NOW ADVISED THAT HE SHOULD GO ON TO MELATONIN MAX WHICH WOULD BE 60 MGMS AT NIGHT FOR 2 NIGHTS THEN INCREASE TO 2 CAPS OF 180 MGMS EVERY NIGHT. THIS IS FRIGHTENING TO US. WHAT IS YOUR OPINION PLEASE. DESPERATE WHITE CELLS 1.8. RED CELLS 2.7, PLATELETS ARE 73. YYYY@YYYY
Thu, 11 Jan 2018
Report Abuse
Oncologist 's  Response
Hi

Melatonin dosages vary depending on the reason this supplement is being used. Dosage guidelines for adult range from 0.3 mg to 5 mg per day. For sleep disorders, most individuals will take 2 – 3 mg one hour prior to bedtime.

Produced from the neurotransmitter serotonin in the brain’s pineal gland, melatonin is a hormone that is released into the blood and cerebrospinal fluid. Secretion of this hormone increases when external light is low. Its release is inhibited by the presence of light.

Using a natural melatonin supplement can help to improve sleep disorders and alleviate insomnia. Taking a small dosage of this supplement in the evening can shorten sleep onset time and improve sleep quality and duration in some cases.

Melatonin (N-acetyl-5-methoxytryptamine) may have additional benefits for health, including acting as an anti-oxidant, improving mood, supporting muscle growth and exhibiting several anti-aging effects. Melatonin dosages are considered safe when used appropriately, but should not be used for longer than six months at a time without doctor supervision.
Melatonin is a hormone that our bodies produce in the pineal gland. It is released when it is dark out and drops off when it is light, suggesting that it is involved in regulating our circadian rhythms and sleep cycles.

In recent years, melatonin has been synthesized in laboratories and released in supplement form. Melatonin tablets have become a popular option as a natural sleep aid with low risk of side effects.

However, high doses of melatonin can result in psychological effects similar to a hypnogogic state. Some users report feeling very relaxed, while others report hallucinations or impaired cognition. Many report serious side effects, such as memory loss, disorientation, confusion and disrupted sleep patterns.
Melatonin is used to for insomnia, shift work disorder, sleep-wake cycle disturbances, jet lag, circadian rhythm disorders in the blind and other sleep disorders.

Research shows that it is effective for alleviating symptoms of primary insomnia and it may have benefits for certain types of secondary insomnia. For these purposes, melatonin is taken in pill or capsule form approximately 30 minutes before bedtime.

Melatonin can also help prevent sleeplessness in hospital settings, where bright light and disturbances can make sleep difficult.

Melatonin supplements also have an anti-anxiety effect and can promote better moods for some users. Recent research suggests this supplement has anti-aging benefits and it demonstrates efficacy as an anti-oxidant.

There is some evidence that melatonin, when applied topically, can prevent sunburn when it is applied before sun exposure.
There is no formal research into whether you can get high from melatonin. There are, however, anecdotal reports of melatonin’s recreational use on forums like Reddit and Erowid.

Users there report a melatonin buzz that comes from taking high dosages of melatonin or combining it with other drugs such as cannabis.

The reports on how much melatonin to take to get high are varied. In one Reddit post, a user says that he and several college-aged friends took anywhere from 15 milligrams to 50 milligrams. All were males weighing between 150 and 180 pounds.

Some consumed only melatonin, while others combined it with cannabis. At least one user was a daily user of the ADHD stimulant medication Adderall, as well. They reported intense intoxication and a feeling similar to extreme drunkenness.

Regards

DR DE
I find this answer helpful

1 Doctor agrees with this answer


Note: For further queries related to kidney problems Click here.
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]
Share on
 

Related questions you may be interested in


Loading Online Doctors....
Does Increasing The Dosage Of Melatonin Max To 180 Mg Dangerous?

Hi Melatonin dosages vary depending on the reason this supplement is being used. Dosage guidelines for adult range from 0.3 mg to 5 mg per day. For sleep disorders, most individuals will take 2 – 3 mg one hour prior to bedtime. Produced from the neurotransmitter serotonin in the brain’s pineal gland, melatonin is a hormone that is released into the blood and cerebrospinal fluid. Secretion of this hormone increases when external light is low. Its release is inhibited by the presence of light. Using a natural melatonin supplement can help to improve sleep disorders and alleviate insomnia. Taking a small dosage of this supplement in the evening can shorten sleep onset time and improve sleep quality and duration in some cases. Melatonin (N-acetyl-5-methoxytryptamine) may have additional benefits for health, including acting as an anti-oxidant, improving mood, supporting muscle growth and exhibiting several anti-aging effects. Melatonin dosages are considered safe when used appropriately, but should not be used for longer than six months at a time without doctor supervision. Melatonin is a hormone that our bodies produce in the pineal gland. It is released when it is dark out and drops off when it is light, suggesting that it is involved in regulating our circadian rhythms and sleep cycles. In recent years, melatonin has been synthesized in laboratories and released in supplement form. Melatonin tablets have become a popular option as a natural sleep aid with low risk of side effects. However, high doses of melatonin can result in psychological effects similar to a hypnogogic state. Some users report feeling very relaxed, while others report hallucinations or impaired cognition. Many report serious side effects, such as memory loss, disorientation, confusion and disrupted sleep patterns. Melatonin is used to for insomnia, shift work disorder, sleep-wake cycle disturbances, jet lag, circadian rhythm disorders in the blind and other sleep disorders. Research shows that it is effective for alleviating symptoms of primary insomnia and it may have benefits for certain types of secondary insomnia. For these purposes, melatonin is taken in pill or capsule form approximately 30 minutes before bedtime. Melatonin can also help prevent sleeplessness in hospital settings, where bright light and disturbances can make sleep difficult. Melatonin supplements also have an anti-anxiety effect and can promote better moods for some users. Recent research suggests this supplement has anti-aging benefits and it demonstrates efficacy as an anti-oxidant. There is some evidence that melatonin, when applied topically, can prevent sunburn when it is applied before sun exposure. There is no formal research into whether you can get high from melatonin. There are, however, anecdotal reports of melatonin’s recreational use on forums like Reddit and Erowid. Users there report a melatonin buzz that comes from taking high dosages of melatonin or combining it with other drugs such as cannabis. The reports on how much melatonin to take to get high are varied. In one Reddit post, a user says that he and several college-aged friends took anywhere from 15 milligrams to 50 milligrams. All were males weighing between 150 and 180 pounds. Some consumed only melatonin, while others combined it with cannabis. At least one user was a daily user of the ADHD stimulant medication Adderall, as well. They reported intense intoxication and a feeling similar to extreme drunkenness. Regards DR DE