Does smoking weed affect your thyroid? I find that after I smoke a good amount of marijuana or I take a big hit, my throat begins to burn and I have to rapidly swallow to help aid in the pain. My throat starts to slightly throb and my mouth becomes very dry. What are the causes for this? Is there anyway I can prevent it? I use marijuana to self medicate and it really helps, so I m looking for a solution where I don t have to give it up. Thanks!