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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Solitary Plasmacytoma Lead To Multiple Myeloma?

HELLO DOCTOR ,Two month before my husband diagnosed with Solitary bone plasmacytoma ,and he done radiation treatment,i want to know all solitary plasmacytoma lead to multiple myloma,any precaution we need to take for that? His age is 34 ,i want to know the progress time periodSBP to myloma.
posted on Thu, 4 Aug 2016
Twitter Mon, 22 Aug 2016 Answered on
Twitter Tue, 23 Aug 2016 Last reviewed on
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General & Family Physician,  's  Response
Plasmacytoma is a tumor of plasma cells but its manifestation is as localized tumor as compared to multiple myeloma which is also a plasma cell malignancy and manifest in a generalized manner. Solitary plasmacytoma is treated by radiation. But it may relapse in future. The majority of patients with solitary plasmacytoma develop myeloma. But when solitary plasmacytoma will convert into myeloma is uncertain and variable. It is difficult to estimate time. It develops early in patients who are more than 60 years old.
Precautions
1.     Be watchful for any bone pain or bone fracture
2.     Regular estimate blood hemoglobin level. A falling trend is serious
3.     Regularly check serum creatinine and calcium
4.     Regularly do R/E of urine for Bence Jones urinary protein in urine
5.     Be careful if getting repeated infection
6.     Regularly check serum or urinary level of monoclonal protein
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Does Solitary Plasmacytoma Lead To Multiple Myeloma?

Plasmacytoma is a tumor of plasma cells but its manifestation is as localized tumor as compared to multiple myeloma which is also a plasma cell malignancy and manifest in a generalized manner. Solitary plasmacytoma is treated by radiation. But it may relapse in future. The majority of patients with solitary plasmacytoma develop myeloma. But when solitary plasmacytoma will convert into myeloma is uncertain and variable. It is difficult to estimate time. It develops early in patients who are more than 60 years old. Precautions 1. Be watchful for any bone pain or bone fracture 2. Regular estimate blood hemoglobin level. A falling trend is serious 3. Regularly check serum creatinine and calcium 4. Regularly do R/E of urine for Bence Jones urinary protein in urine 5. Be careful if getting repeated infection 6. Regularly check serum or urinary level of monoclonal protein Thanks