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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Done Lab Work For Lupus. Does This Mean My ANA Was Positive?

I have recently had lab work for lupus , I received lab results back with no explanation. ANA profile; ana= 24 (0-100AU/ml); ssa 8( 100 AU/ml); ssb= 6 ( 100 AU/ml); sm= 9( 100 AU/ml); RNP =22( 100 AU/ml); SCI-70 =24( 100 AU/ml); JO-1= 8 ( 100 AU/ml); DSDNA = 0( 100 AU/ml);CENT B = 3( 100 AU/ml); HISTONE = 7( 100 AU/ml); Rheumatoid factor 50.1 ( 6.0 IU/ml)A Can someone please tell me does this mean that my ANA was positive or not in normal range. and if this anything to be concerned about. I am thinking not since the doctor just mailed the pages with nothing stating if I needed a follow up or if there is nothing to worry about and the pages are for my records.
Tue, 30 Oct 2012
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Rheumatologist 's  Response
your blood reports just suggest a high normal rheumatoid factor and it does not suggest anything more. If you have any joint symptoms you need further followup and investigations.The chance of people with positive rheumatoid factor developing Rheumatoid arthritis is more.
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Allergist and Immunologist Dr. Sujoy Khan's  Response
Hello,
The test that you had was an ANA ELISA that is being done in many laboratories replacing the ANA slide test that gives you a qualititative report (i.e., positive or negative). The ANA ELISA test gives you a number for an answer and the normal range is given in brackets next to it. All these test results show that specific autoantibodies are absent in your blood and therefore the chances of an autoimmune or connective tissue disease (like SLE) are very low. Obviously this test (if positive) is just one of 11 criteria for SLE, so you need to ask your doctor why he did the test.
The low positive rheumatoid factor is non-specific and the more specific test for rheumatoid arthritis is the anti-CCP antibody test.
Thanks.
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Rheumatologist Dr. Divya Agarwal's  Response
Hi,
According to this your rheumatoid factor is positive and rest of the labs are normal. Reports dont suggest much, it is more important to see what you have clinically.
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Done Lab Work For Lupus. Does This Mean My ANA Was Positive?

your blood reports just suggest a high normal rheumatoid factor and it does not suggest anything more. If you have any joint symptoms you need further followup and investigations.The chance of people with positive rheumatoid factor developing Rheumatoid arthritis is more.