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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Elevated ALT Level Of 66. History Of Intake Of Xanax For Anxiety, Motrin. Occasional Drinking. Liver And Gallbladder Normal. Suggest

Recently had elevated ALT level of 66, Drink occasionally. Had taken xanax for first time morning of blood text for anxiety. A few days previously I had taken 1.5 g of motrin over a 2 day period. Also had 4 beers 5 days prior to the blood test. All other blood levels were normal. Followed up with an ultrasound that was negative for any liver or gall bladder problems. Tested negative for all hepatitis. Very concerned as to why ALT levels are high. Please help.
posted on Sat, 28 Sep 2013
Twitter Sat, 28 Sep 2013 Answered on
Twitter Sat, 28 Sep 2013 Last reviewed on
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General & Family Physician,  's  Response
Hello,
Thanks for the query to H.C.M. Forum.
Alanine aminotransferase or A L T or S G P T is primarily found in the liver.
However this value of A L T is not so specific but one important point is ratio of AST & ALT AS,
In most acute hepatocellular disorders, the A L T is higher than or equal to the AS T .
An AST:ALT ratio >2:1 is suggestive while a ratio > 3:1 is highly suggestive of alcoholic liver disease.
I am sorry to say so lengthy detail but it was necessary because you have not mentioned the exact ratio of AST and ALT .
In my opinion xanax ( alprazolam ) and motrin ( ibuprofen ) intake didn't play any role in elevation of this enzyme .
Get in blood reports of ALT & AST ratio and upload.
Consult a physician and get his opinion regarding alcoholic liver disease.
Good luck. Dr. HET
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Elevated ALT Level Of 66. History Of Intake Of Xanax For Anxiety, Motrin. Occasional Drinking. Liver And Gallbladder Normal. Suggest

Hello, Thanks for the query to H.C.M. Forum. Alanine aminotransferase or A L T or S G P T is primarily found in the liver. However this value of A L T is not so specific but one important point is ratio of AST & ALT AS, In most acute hepatocellular disorders, the A L T is higher than or equal to the AS T . An AST:ALT ratio 2:1 is suggestive while a ratio 3:1 is highly suggestive of alcoholic liver disease. I am sorry to say so lengthy detail but it was necessary because you have not mentioned the exact ratio of AST and ALT . In my opinion xanax ( alprazolam ) and motrin ( ibuprofen ) intake didn t play any role in elevation of this enzyme . Get in blood reports of ALT & AST ratio and upload. Consult a physician and get his opinion regarding alcoholic liver disease. Good luck. Dr. HET