My son, age 44, has had episodes of sudden onset extreme headache accompanied by rise in B/P as high as 230/130. His normal pressure is 100-110/60-70. IV Morphine didn't touch the headache or B/P but IV Labetalol did bring it down to 140s/90s. He was then given Benadryl and Inapsine IV which resulted in sleep, lowered B/P, and much improvement in headache. He has a headache all the time for which he takes Advil . These are sais to be post concussion syndrome headaches. Could PFO be contributing to this problem? He is otherwise healthy.