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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Have Rashes, Roughness, Losing Tendon Action In Finger. Had Levaquin IV And Nystatin. Allergic Reaction?

I had Levaquin IV 750 mg doses qid for 3 days and then 10 days oral 750 mg bid. Rash over ankles, hands, elbows on day 3 (IV still given) while still in hospital. October 2012. Rash persisted, worse over time, cracking, roughness over Achilles but treated with Clobestol/Nystatin without effect. Now, losing tendon action in finger flexors (Aug/Sept 2013). Had a gram negative pneumonia April 2013 with 10 day ICU stay NOT treated with Levaquin. MD questioning collapse as I am usually in good health. did biopsy and it showed a spongiform non-specific dermatitis. She doesn't think any allergic reaction to any drug can last this long especially as biopsy didn't show eosinophils. Do you have any clinical evidence for how long a reaction like this take place? My primary MD has listed an allergy to Levaquin because of the reaction at the hospital.
Sat, 14 Sep 2013
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Dermatologist 's  Response
Hi drug rash does not persist so long .i think there is no relation of rash and loss of flexion in tendons.drug induced rash subsides as soon as drug is withdrawn or within one week.rule out any connective tissue disorder .use short course of steriods.antihistamine and broad spectrum antibiotic and apply calamine lotion over the rash effected areas
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Have Rashes, Roughness, Losing Tendon Action In Finger. Had Levaquin IV And Nystatin. Allergic Reaction?

Hi drug rash does not persist so long .i think there is no relation of rash and loss of flexion in tendons.drug induced rash subsides as soon as drug is withdrawn or within one week.rule out any connective tissue disorder .use short course of steriods.antihistamine and broad spectrum antibiotic and apply calamine lotion over the rash effected areas