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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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History Of Von Wilebrands. Have Nephrostomy Tubes, Renal Stents, Hydronephric Kidney. Will DVAPP Control Bleeding?

Hi there! I am a 50-yr-old female with history of Von Wilebrands. I have had over 31 pints of donated blood during various surgeries and have almost bled out in surgery 3 times (Emergency C-Section, ureter resection and hysterectomy). I am dealing with right kidney problems (2 nephrostomy tubes/9 renal stents) and my kidney remains hydronephroic (?) and painful keeing me down more than up. Would it be wise for me to consider having it taken out vs. stents/hospital visits/lots of pain? Do you think DVAPP would control the bleeding? Thank you!
Fri, 16 Aug 2013
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Pathologist and Microbiologist,  's  Response
Hello and welcome to HCM,

Von Willebrand disease is managed by DVAPP.
However, during periods of crisis like surgery factor replacement may be required.
Fresh frozen plasma is best suited for replacement of deficient factors.
whole blood infusions can cause volume overload and hypercalcemia.
DVAPP can be used once you tide over the period of crisis.
The best management for the hydronephrotic kidney will depend on your clinical status.
Nephrostomy tubes are temporary and can be taken out once the indication is over.
Stents would help in managing the hydronephrosis for long period.
Stay in touch with your hematologist and nephrologist so that the condition can be jointly managed.

Thanks and take care
Dr Shailja P Wahal


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History Of Von Wilebrands. Have Nephrostomy Tubes, Renal Stents, Hydronephric Kidney. Will DVAPP Control Bleeding?

Hello and welcome to HCM, Von Willebrand disease is managed by DVAPP. However, during periods of crisis like surgery factor replacement may be required. Fresh frozen plasma is best suited for replacement of deficient factors. whole blood infusions can cause volume overload and hypercalcemia. DVAPP can be used once you tide over the period of crisis. The best management for the hydronephrotic kidney will depend on your clinical status. Nephrostomy tubes are temporary and can be taken out once the indication is over. Stents would help in managing the hydronephrosis for long period. Stay in touch with your hematologist and nephrologist so that the condition can be jointly managed. Thanks and take care Dr Shailja P Wahal