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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Can I Safely Potentiate Adderall-XR With Supplements Without Risking Serotonin Syndrome Or Dopamine Crash?

Hello. I have a few questions about adderall in the context of harm reduction and achieving a desired effect through my medication. I am currently taking 25mg of Adderall XR and I would like to potentiate it. I have been taking two supplements daily in order to achieve lowered latent inhibition and increased (but steady) levels of dopamine: 750mg Calcium Bicarbonate and 300mg 5HTP. Before I add to the list of supplements I take, I wanted to get advice from a doctor. What can I do to potentiate Adderall safely (i.e avoiding serotonin syndrome and a dopamine crash ) via supplements? What would be the maximum dosage that you personally would prescribe a patient? And what is the maximum dosage that one should ingest before dialing it back (in mg/kg)?
posted on Thu, 6 Jul 2023
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