Good morning, my mum is being treated for high blood pressure, her dystolic is always above 100, Aveage bp for her is about 180/112 she has been on 10mg ramapril for about 3 years and it hasn t improved it at all, the doctor recently started her on 5mg of bisoprol as her heart rate is also always over 100 her hate rate stableised with this and was always sitting around 70 but it didn t improve her blood pressure so he stopped the bisoprolol and started her on 5mg of amlodopine which still hasn t made a great improvement her blood pressure is still always high as now is her heart rate but the doctor told us it s not safe to take all 3 drugs together is this true? Can you advise what would be the best combination of medication for her to take, im very paranoid about blood pressure as I work in a heart speacialist hospital and see the consequences of it everyday and my mum also has history of stroke and Brian hemmorage in her family.