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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Can Polymyositis Be Treated?

I am suffering from Polymyositis, since one year. My CPK was 2379 before 8 months, Then decreased to 221 last in Aug-17 after IVIG infusion. Now I am on 20 mg. Omnacortil once a day, Tappered from 60 mg. In Oct-17, my CPK found 322. I have taken @ 20 nos. Ampoxilin tab for Coughing / throat infection before test. No chest pain , No arm / shoulder / back pain / No breathing problem. What will be the reason for elevating CPK ? Pl. guide. Thanks... Harsha - F/ 55 yrs.
posted on Sun, 15 Oct 2017
Twitter Sun, 15 Jul 2018 Answered on
Twitter Thu, 19 Jul 2018 Last reviewed on
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Internal Medicine Specialist,  's  Response
Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phosphocreatine kinase, is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and utilizes adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP). So ATP fast utilization tissue like skeletal muscle, brain,retina, other muscle. So elevation of this is a indication for myocardial infraction, myositis, muscular dystrophy etc. It is treated with corticosteroid or Immunosuppressants , IVIG , calcinirin inhibitors etc. Once remission accure need to maintain life long maintenance dose of drug. Please consult your doctor he will examine and treat you accordingly.

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How Can Polymyositis Be Treated?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phosphocreatine kinase, is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and utilizes adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP). So ATP fast utilization tissue like skeletal muscle, brain,retina, other muscle. So elevation of this is a indication for myocardial infraction, myositis, muscular dystrophy etc. It is treated with corticosteroid or Immunosuppressants , IVIG , calcinirin inhibitors etc. Once remission accure need to maintain life long maintenance dose of drug. Please consult your doctor he will examine and treat you accordingly. Hope I have answered your query. Let me know if I can assist you further.