I have a 20-year-old daughter who is experiencing what I consider to be severe anxiety symptoms. We have a STRONG genetic predisposition for anxiety issues as well as depression. (Fortunately- this is the ONLY thing that runs in my family-- no cancer, no high blood pressure, no diabetes, serious illnesses, etc.)... Unfortunately, anxiety is NO SMALL THING. I have had the worst case of it in all of my immediate and extended family, and there are no adequate words to describe what it s like to deal this with disorder. It feels like MASSIVE amounts of adrenaline-- sometimes for long periods of time-- uncontrollably being produced by your body... and the worst part is that sometimes there are triggers that start these anxiety attacks or panic attacks-- but other times, both myself, 1/2 of my siblings --(a clue that this disorder has a genetic-base and biological root-- rather than an environmental trigger in our family or something to do with our upbringing or any dysfunction aspects of our family) -- have had absolutely TOTALLY random anxiety for ABSOLUTELY NO REASON. It is a miserable condition. Now... 1 or my 2 daughters (who has always had some anxiety)... is dealing with college, assignments & homework, a few professors that are extremely difficult for students to deal with, a part time job, a boyfriend, and she is currently about to do a mid-year/ (2nd semester of her Junior college year) transfer to a different University (not large-- mid-size) beginning in January and is preparing for that. Is it any wonder that she s having panic attacks...? Of course not-- this is a very stressful age of life-- I remember it like it was yesterday; however, her family doctor and I do not seem to be able to get a handle on helping her regardless of medications tried, a counselor/ talk-therapist, lots of immediate family support and extended family support... and I guess I just need some advice about the medications that we are trying right now-- the mixture of them -- and the possible side effects that we might run into... (did I mention that my daughter s worrying about the possible side effects of these new medications is causing her even MORE anxiety....?) She has been on 20 mg of Prozac for the past approximately 8 years. We found that Prozac works extremely well with my family members... Zoloft works okay, Paxil is a disaster, (the missing doses hell and the huge amount of possible weight gain!!), and Wellbutrin-- which many of our friends all seem to swear by -- seems to help the depression aspects that my family experiences -- but it also seems to have a rare side effect in my family -- which is that Wellbutrin causes EVEN MORE ANXIETY and makes it completely unmanageable (something about the fact that it works on the other neurotransmitters which help Dopemine levels-- wheras our deficiency seems to almost ALWAYS be in the Seratonin deficiency area... I have a psychiatrist for myself-- (since I ve had anxiety attacks since the age of THREE... And yes, I do remember them well & exactly when they started...and there were no triggers). I ve tried many meds over the years to try to best treat my anxiety as well as my depression (and I ve got some OCD mixed in there too! : / )... so I know a lot about many of them. My psychiatrist and I presently, and have found that the best thing for my biology/ chemistry of my body is 1) 60 mg of Prozac 2) Temazepam for anxiety/ insomnia at bedtime 3) GABA (Neurontin) - small dose - but to keep building it up in my bloodstream to help with the anxiety, and 4th ) Valium - 3 times per day for some serious life issues that I am currently dealing with -- including the recent death of my Father 4 months ago, trying to help my Mother, being a single parent to 1 young adult (the daughter that I am writing about) as well as 1 sixteen-year old daughter, and having gone through a horrible divorce about 2 years ago after a seemingly solid and happy marriage for 28 years. (We plan to take the Valium down to 2 X per day soon... and then to 1X per day after that - in order to avoid the addictive effects). ***I want my 20 year old daughter - with all of this college-age stress, (as well as after-effects of the divorce), to see my own psychiatrist-- since he understands the biology/ chemistry of my family-- however, he has a 6-month waiting list for Intakes/ New Patients ... We can t wait that long. As I said, this daughters is seeing a good counselor/ therapist-- and she is good and helpful, but the anxiety attacks are still serious & not manageable. So her family doctor/ personal physician has tried to prescribe appropriate medications for her. 1) He has upped her dose to 40 mg. 2) He has prescribed Ativan-- ONLY for when the panic attacks/ anxiety becomes EXTREME (he gives her a limited number, of course).... and now he just met with her, and wants to had Buspar(ine) ?? My question is: Does this sound like a good idea...? A good combination of medications-- given her current age, college status, life stressors (transferring colleges to 1 that is an hour away from home), part time work stress, massive amounts of homework, a boyfriend, and this horrible divorce that was just 2 years ago? Also, does this sound like a good combination of meds based on what I ve mentioned about my immediate family s predisposition for these disorders/ imbalances with serotonin and the way that the Family of Meds that include the Wellbutrin kind don t seem to be a good fit for us.....? (isn t Buspar(ine) in the same medication family as Wellbutrin? Thanks for your help, in advance! -Sherry YYYY@YYYY