HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
159 Doctors Online

By proceeding, I accept the Terms and Conditions

Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

HCM Blog Instant Access to Doctors
HCM BlogQuestions Answered
HCM Blog Satisfaction

How Long Does Plan-B Remain In The System For Urinalysis?

Is it possible for plan b to show up on a urinalysis using an advanced immunoassay machine for drug testing ? I ve read that it s just a hormone but my girlfriend and I had unprotected sex and she s on random drug testing and not supposed to take anything without it first being approved. By the way the machine used is in a lab not dipstick tests it has a name and then a number next to it like 2000 I think.
Thu, 11 Aug 2016
Report Abuse
General & Family Physician,  's  Response
Hi,

Thanks for posting in HCM.

I understand your concern.

Plan B contains 1.5 mg of hormone 'levonorgestrel'. It is a synthetic progestogen used for contraception.

As per the information available from various studies, metabolism and excretion of [14C]-levonorgestrel (radio-labelled) after a single 1.5-mg oral dose occurs as follows:
1. Conjugation (sulfates and glucuronides) was the primary metabolic reaction that takes place.
2. Major urinary metabolites seen include 3 alpha-hydroxy-tetrahydrolevonorgestrel, 2 alpha-hydroxylevonorgestrel, 13-ethyl-4-homogonane-3,17-dione, and their corresponding sulfate and glucuronide conjugates.
3. Minor hydroxylated metabolites found in urine include 3-β-hydroxy-, 3 alpha,16 alpha-dihydroxy-, and 3 alpha,16-β-dihydroxy-tetrahydrolevonorgestrels and 16-β-hydroxylevonorgestrel.

The half-life is 24 to 28 hours. Both the parent drug and its metabolites are primarily excreted in the urine. Approximately 45% is excreted in the urine and 32% in feces, mostly as glucuronide conjugates.

Hope the information provided would be helpful.
All the best.
I find this answer helpful
Note: For further follow up on related General & Family Physician Click here.
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]
Share on
 

Related questions you may be interested in


Loading Online Doctors....
How Long Does Plan-B Remain In The System For Urinalysis?

Hi, Thanks for posting in HCM. I understand your concern. Plan B contains 1.5 mg of hormone levonorgestrel . It is a synthetic progestogen used for contraception. As per the information available from various studies, metabolism and excretion of [14C]-levonorgestrel (radio-labelled) after a single 1.5-mg oral dose occurs as follows: 1. Conjugation (sulfates and glucuronides) was the primary metabolic reaction that takes place. 2. Major urinary metabolites seen include 3 alpha-hydroxy-tetrahydrolevonorgestrel, 2 alpha-hydroxylevonorgestrel, 13-ethyl-4-homogonane-3,17-dione, and their corresponding sulfate and glucuronide conjugates. 3. Minor hydroxylated metabolites found in urine include 3-β-hydroxy-, 3 alpha,16 alpha-dihydroxy-, and 3 alpha,16-β-dihydroxy-tetrahydrolevonorgestrels and 16-β-hydroxylevonorgestrel. The half-life is 24 to 28 hours. Both the parent drug and its metabolites are primarily excreted in the urine. Approximately 45% is excreted in the urine and 32% in feces, mostly as glucuronide conjugates. Hope the information provided would be helpful. All the best.