Hi thanks for asking question. Your bother having hepatitis c. He might develop here cirrhosis. Because of cirrhosis variceal bleeding from rectum may present here.For esophageal varices banding can done... As kidney is shutting down suggesting hepatic disease induce functional kidney failure as may be by hepatorenal syndrome. Slurred speech indicating encephalopathy development.... So here prognosis seems poor. Care taken with consultation to surgeon. If need for portal hypertension beta blocker can taken... Take low salt and low fat diet. One tsp licorice with honey can taken. If needed for encephalopathy neomycin or rifaximine like antibiotic taken after estimating blood ammonia level.. Fruits more.like papaiya Take care. Dr.Parth