I am a 51 y/o menopausal occasional ( every 6 month ) break thru vaginal bleeding. As of January I started with a light period every 7 -10 days . I have had a gyn work-up with transvaginal and pelvic US both negative . I am on Estradiol and Progesterone daily. Just recently went on vacation and decided to leave the supplement Biotin 5000 mcg that I take QOD at home and noted the vaginal bleeding stopped .As soon as I returned home I restarted and it the vaginal bleeding has reoccurred . I have tried to do online searches but do not find any info linking Biotin to bleeding .Are you aware of this as S/E ?