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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How To Get Pregnant?

32 yr old female trying to be surrogate. Weight 138 and 5 ft 5 in tall. 2 easy non-complicated natural pregnancies and deliveries in 2009 and 2011, got pregnant both times on 1st try. With recent surrogacy journey, in 3 attempts (and 3 cancelled cycles) lining could not get above 7mm and intermediate pattern (B rating) and saw scant fluid on 2 instances (1 recent mock cycle and one prior cycle months ago). Any thoughts on why any of this is happening? I even had a hysteroscopy with D&C to rule out complications and give me clean slate , but apparently it didn t help, although on a positive note it showed everything looked good and results came back normal. Any advice and opinions welcome. I really feel like I was meant to be a surrogate and really want to help someone wanting a baby and am so discouraged that this isn t working. Wondering if something could be wrong that hasn t been seen yet? Oh yeah, and it was on 2 mg estradiol for the first week each cycle, then it was upped to 4mg/day for remaining cycle days. Started off the entire process with 1 lupron depot shot only and never went off the estradiol. Thank you!
posted on Fri, 23 May 2014
Twitter Sun, 22 May 2016 Answered on
Twitter Mon, 23 May 2016 Last reviewed on
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OBGYN,  's  Response
Hallow Dear,

I do appreciate your approach to help someone with surrogacy.

After going through your detailed history, the only subnormal finding I could get was your endometrial thickness. Endometrium between 9 and 13 mm thickness is most conducive for implantation of fertilized ovum; while your endometrium is not crossing the figure of 7 mm. To increase the endometrial thickness, you have been put on Estradiol and Lupron. Still it has not given satisfactory results.

I would suggest you first to downregulate the Oestrogen and the go for Lupron. We have found very good results by this regime. Of course, before that, please get your Hysteromicroscopy performed to find out whether there is any pathology in the endometrium.

I hope this guides you appropriately.

Dr. Nishikant Shrotri
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How To Get Pregnant?

Hallow Dear, I do appreciate your approach to help someone with surrogacy. After going through your detailed history, the only subnormal finding I could get was your endometrial thickness. Endometrium between 9 and 13 mm thickness is most conducive for implantation of fertilized ovum; while your endometrium is not crossing the figure of 7 mm. To increase the endometrial thickness, you have been put on Estradiol and Lupron. Still it has not given satisfactory results. I would suggest you first to downregulate the Oestrogen and the go for Lupron. We have found very good results by this regime. Of course, before that, please get your Hysteromicroscopy performed to find out whether there is any pathology in the endometrium. I hope this guides you appropriately. Dr. Nishikant Shrotri