Hi Thanks for your query You seem to be having Candidiasis in the toe web space region. Do not apply any kind of oils / moisturizing lotion over the affected area . Wear open footwear so as to decrease sweating. Just give warm saline compresses over the affected area twice a day and then apply an antifungal cream. Something like clotrimazole cream helps in most cases. Also , you will need to take oral antifungals 2 weeks. In case of severe itching, take some antihistamine once a day . If inspite of the above measures, the lesions continue to persist or increase , then you might have to see a dermatologist for proper assessment and management . Hope it helps Dr Geetika Paul