Back in December, I had a blood and urine test performed which showed an elevated liver enzyme level. A couple of months later I began to notice swelling on both of lower legs, ankles, and tops of my feet, accompanied by a heated red rash, tightness, and limited mobility. I went to see my general practitioner who requested another blood & urine test. Elevated liver enzymes count came back again. He referred me to a gastrointestinal and a kidney specialist. The gastroinstestinal specialist requested more blood tests, an ultra sound of the liver and intestinal organs, and I also had a liver biopsy. The ultra sound came back clear. I also had a colonscopy which came back clear. The liver biopsy showed sign of an infection but the pathologist was unsure what it could be. The gastrointestinal dr asked for another blood test and the markers for hepititis all came back negative except one - ana. The kidney specialist ruled out anything on his part because the lab erroroneously entered 100 to my age when determining the blood work results. However he referred me to a vein specialist to do an ultra sound on my legs. The ultra sound came back normal. The gastrointestinal dr is saying that it is possibly a form of autoimmune hepititus though is not sure and would like to see me to begin a prescription for it. My question is this: I have to two moles - one on each lower leg in the general inflamed areas are. Could melanoma cause all the symptoms and test results seen thus far? inflamation, redness, soreness of both legs, swelling, ANA positive marker, and an elevated liver enzyme count? Thank you in advance. Jeanette