I Have Been Suffering From Depression And Anxiety For 30

I have been suffering from depression and anxiety for 30 years and I am on venlafaxine and take 3.-75 daily previously have taken Prozac seroxet I am a 56 year old female with ADHD and a few other physical problems now I have been suffering from lathaljict behaviour very low self-esteem anger completely negative do not look after my home any more and stressed all the time and I attend a physicaytist every 6 mouths should I take different drugs