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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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I Want To Know Does Primolut N Has Any Adverse Effect On The Fetus?

i took primolut N for 6 days. i was not aware that i was pregnant. My last MC date was 17-aug-10 and i took primolute N ( 1 tab / day) from 11-sep to 15-sep. When i did pregnancy test on 30-sep-10 , i came to know that i was pregnent. I want to know does premolute N has any adverse effect on foetus? is it advisable to continue pregnancy?
Mon, 21 Dec 2015
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OBGYN 's  Response
Hello,
I can understand your worry, but, I would like to say, the dosage you have taken is very little and also very early in your pregnancy. Hence, the chances of affecting the embryo are very minimal. Norethisterone can cause virilization of a female fetus when used in higher doses, if used at 7-8 weeks of pregnancy, as this is the time of organogenesis of gonads, where there is hormone sensitivity. It is a category D drug contraindicated in pregnancy. In view of these facts, you can decide on the future of the pregnancy if you can get the fetal DNA tests done to detect any malformations early enough. If no abnormal test results come, you can continue with the pregnancy with regular monitoring. Hope you find this information useful. Wish you good health.
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I Want To Know Does Primolut N Has Any Adverse Effect On The Fetus?

Hello, I can understand your worry, but, I would like to say, the dosage you have taken is very little and also very early in your pregnancy. Hence, the chances of affecting the embryo are very minimal. Norethisterone can cause virilization of a female fetus when used in higher doses, if used at 7-8 weeks of pregnancy, as this is the time of organogenesis of gonads, where there is hormone sensitivity. It is a category D drug contraindicated in pregnancy. In view of these facts, you can decide on the future of the pregnancy if you can get the fetal DNA tests done to detect any malformations early enough. If no abnormal test results come, you can continue with the pregnancy with regular monitoring. Hope you find this information useful. Wish you good health.