I'M 60 years old and have frequent leg aches that I have to take Advil for. A little history: I have always had them, been checked as a child for rheumatoid arthritis, and lots of other stuff, fortunately I'm fine in all that. My grandmother had them, my mother had them, my daughter and granddaughter have them. (Seems like all the females get them). My son and his son have had a few of them over the years. It's not a constant ache, just maybe once or twice a week and have to take Advil to get it to go away and stay gone. Other than that, I'm very healthy.