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Is AS Probable In A Patient With A Negative Test For HLA-B2?
Hello sir,2days back I went to rheumatologist doctor ..he confirmed that I have ankylosis spodilytis,he had seen mri&ct scan,he suggested me for some blood tests esr,cpp,sgpt,creatine all are normal now he is planning for hlab27...but it is negative now can u tell me what is my exact problem
posted on
Tue, 13 Oct 2015
Medically reviewed by
Ask A Doctor - 24x7 Medical Review Team
Tue, 31 Mar 2020
Answered on
Tue, 31 Mar 2020
Last reviewed on
Hi,
It is suggestive of seronegative spondyloarthropathies. Ankylosing spondylitis is strongly associated with the HLA-B27 gene and it is positive in over 90% of patients. A negative test could be found in approximately 10% is suggestive of seronegative spondyloarthropathies.
Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Mohammed Taher Ali, General & Family Physician
It is suggestive of seronegative spondyloarthropathies. Ankylosing spondylitis is strongly associated with the HLA-B27 gene and it is positive in over 90% of patients. A negative test could be found in approximately 10% is suggestive of seronegative spondyloarthropathies.
Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Mohammed Taher Ali, General & Family Physician
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