Sign-in to Ask A Doctor - 24x7
OR
Sign in with GoogleGet your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
Is Gemzar The Right Medicine For Cutaneous T-cell Lymphoma?
I have cutaneous T-cell Lymphoma and am taking Gemzar one day a week for three weeks, follow up with the Oncologist on the fourth. So far no really bad side effects. In your opinion, is this a good treatment for CTCL? I must add that I ve tried every medicine knowm for this. My type of CTCL is Mycosis Fungoides. Sorry this is lenghthy but these things are difficult to put into words. I have some good effects with the Chemo, such as I don t scratch my skin bloody in my sleep,
Fri, 11 May 2018
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.
Mycosis Fungoides is the most common type of cutaneous T cell lymphoma.
There are studies that reported and confirmed the early efficacy of gemcitabine (Gemzar) in advanced-stage cutaneous T-cell lymphoma. However, results contradict the safety profile of gemcitabine previously reported and underline the high incidence of severe complications including visceral and cutaneous involvement.
Cutaneous T cell lymphomas are treated with skin-directed or systemic therapies including retinoids like bexarotene. In advanced stages, histone deacetylase inhibitors, interferons or chemotherapeutic agents have been used with variable efficacy.
In my opinion, Gemzar is a good treatment. However, there are newer treatment options available for cutaneous T cell lymphoma including monoclonal antibodies (Alemtuzumab, brentuximab vedotin and mogamulizumab).
Hope I have answered your query. Let me know if I can assist you further.
Regards,
Dr. Narender Kumar
I have reviewed your query and here is my advice.
Mycosis Fungoides is the most common type of cutaneous T cell lymphoma.
There are studies that reported and confirmed the early efficacy of gemcitabine (Gemzar) in advanced-stage cutaneous T-cell lymphoma. However, results contradict the safety profile of gemcitabine previously reported and underline the high incidence of severe complications including visceral and cutaneous involvement.
Cutaneous T cell lymphomas are treated with skin-directed or systemic therapies including retinoids like bexarotene. In advanced stages, histone deacetylase inhibitors, interferons or chemotherapeutic agents have been used with variable efficacy.
In my opinion, Gemzar is a good treatment. However, there are newer treatment options available for cutaneous T cell lymphoma including monoclonal antibodies (Alemtuzumab, brentuximab vedotin and mogamulizumab).
Hope I have answered your query. Let me know if I can assist you further.
Regards,
Dr. Narender Kumar
I find this answer helpful
1 Doctor agrees with this answer
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer.
For a more detailed, immediate answer, try our premium service
[Sample answer]
Related questions you may be interested in
Loading Online Doctors....