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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Vitiligo A Hereditary Disease And Chances Of Affecting The Future Generations?

Hello
I want to know about vitiligo skin disease.
(In my family no one has vitiligo)I am going get married and the girl has vitiligo spots on eyes.
As by I came to know that some percent of vitiligo disease hereditary.So, is there any chances of getting the same disease to children in future.
Mon, 1 Sep 2014
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Radiologist,  's  Response
Hi,
Thanks for writing in.

Variations in the NLRP1 and PTPN22 genes have been associated with an increased risk of developing vitiligo. Studies have suggested that variations in a number of other genes may also affect the risk of vitiligo, but most of these associations have not been confirmed.

Vitiligo sometimes runs in families, but the inheritance pattern is complex since multiple causative factors are involved. About one-fifth of people with this condition have at least one close relative who is also affected

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Note: For detailed guidance on genetic screening consult a genetics specialist
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Is Vitiligo A Hereditary Disease And Chances Of Affecting The Future Generations?

Hi, Thanks for writing in. Variations in the NLRP1 and PTPN22 genes have been associated with an increased risk of developing vitiligo. Studies have suggested that variations in a number of other genes may also affect the risk of vitiligo, but most of these associations have not been confirmed. Vitiligo sometimes runs in families, but the inheritance pattern is complex since multiple causative factors are involved. About one-fifth of people with this condition have at least one close relative who is also affected