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Dr. Andrew Rynne
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Dr. Andrew Rynne

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Is Chronic Back Pain And Pressure In Head Sign Of Lupus?

I have recently been seeing several doctors over the last 8 mothts due to some odd symptoms, one pupil was VERY dialated and the other was fine. I saw a Neurologist, had the CT Scan and the MRI, and a battery of blood tests (including the one for siphilys) Everything came out clear except that my ANA was abmormally high. I was then sent to a rheumatologist who did another blood test and seems to think I may have Lupus, but it is not conclusive. I am in Wait and See mode and have had a few things pop up and I m not sure if it is connected to the Lupus possiblitiy? or is it something else that I should get checked out? or am I over sensitive to symptoms because of the possibility of Lupus? I m now having cronic lower back pain that is worse in the morning and gets a little better as I move through the day (I ve been taking advil), aslo when I m lying in bed and move to look above my head, I feel a painful pressure in my head that goes away once I lie flat and I have been putting on a little more weight than normal for me. I d appreciate your opionion.
Mon, 8 Sep 2014
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Internal Medicine Specialist 's  Response
Hi,

Thank you for your query. I can understand your concerns.





Systemic Lupus Erythematosus (SLE) does not involve axial joints i.e spinal joints giving rise to chronic low back pain.
There are many conditions associated with positive ANA.
Anti-double- stranded DNA (anti-ds-DNA)-more specific for the diagnosis of SLE and can be detected by radio-immuno-assay. Predictive value of a positive test is >90 % for SLE if present in high titer.
SLE can cause organic psychosis, neurosis,Cranial nerve involvement. That can explain pupillary abnormality.
There is a possibilty of overlap syndrome/mixed connective tissue disease (MCTD) .
I suggest you to undergo the folowing tests:
Serum anti-U1RNP antibody
Thyroid function test : serum free T3,freeT4 & TSH assay, as you are gaining weight.

Regards

Dr. T.K. Biswas M.D.
Mumbai
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Is Chronic Back Pain And Pressure In Head Sign Of Lupus?

Hi, Thank you for your query. I can understand your concerns. Systemic Lupus Erythematosus (SLE) does not involve axial joints i.e spinal joints giving rise to chronic low back pain. There are many conditions associated with positive ANA. Anti-double- stranded DNA (anti-ds-DNA)-more specific for the diagnosis of SLE and can be detected by radio-immuno-assay. Predictive value of a positive test is 90 % for SLE if present in high titer. SLE can cause organic psychosis, neurosis,Cranial nerve involvement. That can explain pupillary abnormality. There is a possibilty of overlap syndrome/mixed connective tissue disease (MCTD) . I suggest you to undergo the folowing tests: Serum anti-U1RNP antibody Thyroid function test : serum free T3,freeT4 & TSH assay, as you are gaining weight. Regards Dr. T.K. Biswas M.D. Mumbai