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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Intake Of Antihistamine Safe While On Narcotics?

IIs it o.k. to take a mild over the counter antihistamine while on narcotics? I currently take Morphine 60 mg extended release twice a day. Four times a day 10 mg. oxycontin for break away pain. I have alka seltzer plus. In the past that has helped my symptoms. Thanks
posted on Sat, 3 May 2014
Twitter Fri, 30 May 2014 Answered on
Twitter Sat, 31 May 2014 Last reviewed on
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General & Family Physician 's  Response
Hello
You didn't mention the name of antihistamine , so I am writing down about few antihistamine ( popular ).
Ceterizine , if taken together with morhine may potentiate effect of antihistamine.
.
Chlorpheniramine maleate may potentiate the sedative effect of opiod ( morphine & oxycontine).
Clemastine may potentiate the sedative effects of cns depressant ( morphine).
Usually all the antihistamine depress the cns with morphine ( opiod drugs ).
So please be careful.
Good luck.
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Is Intake Of Antihistamine Safe While On Narcotics?

Hello You didn t mention the name of antihistamine , so I am writing down about few antihistamine ( popular ). Ceterizine , if taken together with morhine may potentiate effect of antihistamine. . Chlorpheniramine maleate may potentiate the sedative effect of opiod ( morphine & oxycontine). Clemastine may potentiate the sedative effects of cns depressant ( morphine). Usually all the antihistamine depress the cns with morphine ( opiod drugs ). So please be careful. Good luck.