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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Normal To Have Intermittent Fever, Conjunctival Infection, Retinal Detachment And Cardiac Murmur While Suffering From Syphilis?

17 yr old female with history of multiple sexual partners and a therapeutic abortion at 14 yrs old presented with fever, rash generalized fatigue, and acute pain in the left eye. In the last 2 months she has lost 12 kg in weight and reports an intermittent fever with fatigue of the same duration. upon physical exam, She appears ill, has marked conjunctival infection, a tender sclera with palpation, and left retinal detachment with some periorbital swelling. Other physical examination is unremarkable, although she does have prominent nontender cervical nodes. There is also swelling of the inguinal nodes, a macular rash (small, flat spots) on the thigh, and a faint cardiac murmur in the upper chest. . HIV tests were negative, but a serologic test for syphilis was positive, although a hemagglutination test for Treponema pallidum was negative. Urine showed 2+ protein, some red blood cells, and some hyaline casts. Blood screen shows hemoglobin at 80%, with a lymphocyte count of 20% of normal and low platelets. The chest radiograph was normal.
Thu, 2 Jan 2014
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  User's Response
HI
Thank for asking to HCM
It is really sad to know this history, positive syphilis infection can interfere with every system of body, the manifestation and the pathophysiology is depends upon the bacterial load, but looking to the history, her clinical course of disease have involved crucial organs, I think she must be in need of intensive treatment, and the best drug would be penicillin in full fledge regime to save her from morbidity, take a intensive care of her, bye.
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Is It Normal To Have Intermittent Fever, Conjunctival Infection, Retinal Detachment And Cardiac Murmur While Suffering From Syphilis?

HI Thank for asking to HCM It is really sad to know this history, positive syphilis infection can interfere with every system of body, the manifestation and the pathophysiology is depends upon the bacterial load, but looking to the history, her clinical course of disease have involved crucial organs, I think she must be in need of intensive treatment, and the best drug would be penicillin in full fledge regime to save her from morbidity, take a intensive care of her, bye.