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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Safe To Have Anastrozole Instead Of Temaxafine For Breast Cancer?

I have been taking temaxafine for 3 years and my doctor has changed my medication to letrozole. After taking it for 1 month I had a lot of side affect like sore chest,heart pumping out of my chest,terrible night sweats,nightmares,sore ankle,exaustion, sore neck, sharp pain in the back of the neck if taking deep breath and feeling very unwell..Doctor wants to change my medication now to anastrozole. I would like to know what you think.Would I be better off to go back to temaxafine since the side effects were mimimul and ok?
posted on Sat, 15 Nov 2014
Twitter Thu, 1 Jan 2015 Answered on
Twitter Fri, 2 Jan 2015 Last reviewed on
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Oncologist, Surgical,  's  Response
First of all, you should be post menopausal (your menses must have stopped) for you to take either letrozole or anastrazole. If you are not postmenopausal then you should stick to only tamoxifen and no other drug. Also, your bones should be in a healthy condition before starting either of the 2 drugs. For this get a bone densitometry done and if normal only then start letro/anastrazole. If not then continue tamoxifen. By the way, all 3 drugs are equally effective in controlling cancer and any one can be taken.
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Is It Safe To Have Anastrozole Instead Of Temaxafine For Breast Cancer?

First of all, you should be post menopausal (your menses must have stopped) for you to take either letrozole or anastrazole. If you are not postmenopausal then you should stick to only tamoxifen and no other drug. Also, your bones should be in a healthy condition before starting either of the 2 drugs. For this get a bone densitometry done and if normal only then start letro/anastrazole. If not then continue tamoxifen. By the way, all 3 drugs are equally effective in controlling cancer and any one can be taken.