Is It Safe To Take Espazine Plus And Zapiz Without Regular Checks?

Sir, I wanted your advice about my husband Mr Rajesh Nigam (worked as Area Manager in Torrent Pharma) and undergone your treatment in 2001. He his taking 2 mg Espazine Plus & 0.25mg Zapiz sometime 0.25restyle. I am worried about his health as he not gone for checkup recently ? Can u Guide me