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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Safe To Take Modafinil And Wellbutrin For Sleep Apnea And Fatigue?

Mu puminologist decided, after multiple tests from other respected physicians, that my issue with central sleep apnea and day long fatigue is probably central sleep apnea (120 of methadone daily). After a few weeks of mastering the mask, Sleep patterns are much better, and I feel like I SHOULD be feeling better, but the basic :symptoms persist: read-sleep-read-sleep-rad-sleep. Get up in mornin/ feelin ok. eat good breakfast, read paper and start sinking back towards bed. cup of coffee finishes me off. blood pressure 126/90. I just added welbutrin and do feel better. but my symptoms and behaviors are essentially the same. I also have atrial fib. I m sleeping better most night under the mask. I recently added 150mg Welbutrin and 25mg of madafinil 3-4 times daily as needed. That s when the shakes added.I am 75 years old and have always been very active, walking 3-4 miles most days and lotta moving. The sudden aging or sudden fatique syndrome) hit me out of the blue. Middle of one pm I suddenly was habng a problem climbing one flight of stairs. appreciatie any tips, procedures, etc. you can suggest. thank you, paul cummins marietta, ga.
Fri, 12 Jun 2020
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General Surgeon 's  Response
Hello,

As per my clinical experience, the central sleep apnea consists of problem with oxygen supply to parts of body due to central cause. Guidelines for better management:
- Continuous positive airway pressure
- Avoidance of sedatives and alcohol
- Weight control and obesity management

The Modafinil is a CNS stimulant drug and has to be discussed for pros and cons with your treating physician. The Wellbutryn is sedative hypnotic and hence not recommended in patient with sleep apnea.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Bhagyesh V. Patel, General Surgeon
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Is It Safe To Take Modafinil And Wellbutrin For Sleep Apnea And Fatigue?

Hello, As per my clinical experience, the central sleep apnea consists of problem with oxygen supply to parts of body due to central cause. Guidelines for better management: - Continuous positive airway pressure - Avoidance of sedatives and alcohol - Weight control and obesity management The Modafinil is a CNS stimulant drug and has to be discussed for pros and cons with your treating physician. The Wellbutryn is sedative hypnotic and hence not recommended in patient with sleep apnea. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Bhagyesh V. Patel, General Surgeon