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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Low HCG Level During First Few Weeks Of Pregnancy Normal?

Hello Doctor. My wife is 4-5 weeks pregnant and her HCG BETA, FREE, SERUM@(CLIA) shows 24 ng/mL. Is she having normal pregnancy? You can refer https://www.lalpathlabs.com/SampleReports/B151.pdf for range by this specific lab. Thanks in advance for your help!
Thu, 31 Dec 2015
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General & Family Physician,  's  Response
Hi,
Thanks for posting in HCM.
The hormone human chorionic gonadotropin (known as beta-hCG) is produced during pregnancy. Its levels can first be detected in blood by about 11 days after conception and about 12-14 days after conception in urine.
Typically, hCG levels will double every 48 to 72 hours. The level will reach its peak in the first 8-11 weeks of pregnancy and then will decline and level off for the remainder of the pregnancy.
The values suggested by you of 24 ng/mL should be alright for about 4 to 5 weeks of pregnancy. It should start doubling and reach between 90 and 100 ng/mL values by 8 weeks.
Around 5 weeks, the gestational sac is often the first thing that most transvaginal ultrasound (TVS) can detect. Also, within this time period, a yolk sac can be seen inside the gestational sac.
Further, to know about the viability of pregnancy, appearance of heart beat by around 7 to 8 weeks of gestation has to be detected.
Hope the information provided would be helpful.
All the best.
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Is Low HCG Level During First Few Weeks Of Pregnancy Normal?

Hi, Thanks for posting in HCM. The hormone human chorionic gonadotropin (known as beta-hCG) is produced during pregnancy. Its levels can first be detected in blood by about 11 days after conception and about 12-14 days after conception in urine. Typically, hCG levels will double every 48 to 72 hours. The level will reach its peak in the first 8-11 weeks of pregnancy and then will decline and level off for the remainder of the pregnancy. The values suggested by you of 24 ng/mL should be alright for about 4 to 5 weeks of pregnancy. It should start doubling and reach between 90 and 100 ng/mL values by 8 weeks. Around 5 weeks, the gestational sac is often the first thing that most transvaginal ultrasound (TVS) can detect. Also, within this time period, a yolk sac can be seen inside the gestational sac. Further, to know about the viability of pregnancy, appearance of heart beat by around 7 to 8 weeks of gestation has to be detected. Hope the information provided would be helpful. All the best.