Good Day and thank you for being with Healthcare Magic! Having a 28 grams prostate gland is expected for your age of 50. I would recommend doing a serum PSA to screen for prostate cancer. Otherwise if you are generally happy with how you urinate? Do you have urinary frequency (urinating within 2 hours or less) ? Urinary urgency ? waking up more than twice per night to urinate? having a weak stream or urine? having interrupted urination and straining during urination? These are symptoms of prostate problems or BPH and fairly common among men above age 50. if you have one or more of these symptoms I would suggest consulting with a urologist so he can do a digital rectal examination (DRE) to palpate the prostate for any nodulations and to give you a prescription for your prostate and improve your urination (e.g. tamsulosin, terasozin ...) If you re urination is okay and you are not suffering from any of the above mentioned urinary symptoms then your enlarged prostate is not causing any clinical consequence to you. We see patient with big prostates with no symptoms and we also see some patients with relatively smaller prostates that are symptomatic. I hope I have succeeded in providing the information you were looking for. Please feel free to write back to me for any further clarifications at: http://www.HealthcareMagic.com/doctors/dr-manuel-c-see-iv/66014 I would gladly help you. Best wishes. Regards, Manuel C. See IV, M.D. DPBU FPUA