My husband has Parkinson s Disease, at least Stage 3, going on Stage 4. This past week he has become increasingly confused and paranoid. He does take Seraquel, 50 mg every evening. I am a retired RN, and do know that this is a part of the Parkinson s progress. Because he was so totally changed, I have given him an additional dose of 25mg of the Seraquel in the AM with good response the last two days. Do you have any suggestions for additional medication to help. We have an appointment with his Neurologist tomorrow, but I feel guilty in having given him this extra dose without his MD knowing, even though it s only been 3 days and with a good response. Thanking you in advance for any input you can give, Claire Elliott