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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Transplantation The Only Option For Diagnosed NSIP?

I had a lung biopsy done and the diagnosis is NSIP. My pulmonary doctor gave me prednisone, mycophenolate and sulfamethox and I have to get blood work done every 2 weeks for 2 months. My question is; if these meds don t work is my only option transplantation? I m sorry I didn t know is would cost me to ask a question. thanks anyway.
Fri, 17 Apr 2015
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General & Family Physician,  's  Response
Hello and welcome.

Your prognosis, treatment depends on the type of NSIP you have. Whether cellular or fibrotic. Cellular NSIP has a better prognosis and most patients respond to corticosteroid therapy, and rarely require immune-suppressants. Whereas, the fibrotic type carries a risk for failure to steroid therapy and have a higher mortality rate, requiring transplant surgery.

So yes, if you do not respond to corticosteroids and immune-suppression, we may have to start looking out for a donor lung.

Best wishes.
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Is Transplantation The Only Option For Diagnosed NSIP?

Hello and welcome. Your prognosis, treatment depends on the type of NSIP you have. Whether cellular or fibrotic. Cellular NSIP has a better prognosis and most patients respond to corticosteroid therapy, and rarely require immune-suppressants. Whereas, the fibrotic type carries a risk for failure to steroid therapy and have a higher mortality rate, requiring transplant surgery. So yes, if you do not respond to corticosteroids and immune-suppression, we may have to start looking out for a donor lung. Best wishes.