Lung Infection, Fever, Night Swelling, Low WBC, RBC After Chemotherapy For Chronic Lymphocytic Leukemia. No Improvement With Antibiotics, Colstim Injection. What Is The Reason?
My mother is a patient of Chronic Lymphocytic lukemia.After her 5th cycle of Chemotherapy which is Bendamustine & Retuximab regimn she is suffering from fever & lungs infection.As the oral antibiotics were not working doctor advised her to get admitted in hospital.As the WBC & RBC were low,she was given 20 colstim injection & 2 packed cells.Now she is still in the hospital & she is suffering from night swelling.Can u please tell me the reason of this??
Bendamustine is notorious in causing bone marrow supression and low counts. low counts in turn make her prone to infections. her present state is due to infectious complications. Since bendamustine and rituximab is now an approved therapy for CLL, patients are given this treatment and risk of infection is always present when the counts drop. treatment for this present condition is with appropriate antibiotics and other supportive medication. Colstim helps in hastening blood counts by one or two days but understand that colstim doesnt do miracles. counts need to improve on their own. her condition would be reverted to normal only after improvement in blood counts. She needs to be supported with antibiotics till then
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Lung Infection, Fever, Night Swelling, Low WBC, RBC After Chemotherapy For Chronic Lymphocytic Leukemia. No Improvement With Antibiotics, Colstim Injection. What Is The Reason?
Bendamustine is notorious in causing bone marrow supression and low counts. low counts in turn make her prone to infections. her present state is due to infectious complications. Since bendamustine and rituximab is now an approved therapy for CLL, patients are given this treatment and risk of infection is always present when the counts drop. treatment for this present condition is with appropriate antibiotics and other supportive medication. Colstim helps in hastening blood counts by one or two days but understand that colstim doesnt do miracles. counts need to improve on their own. her condition would be reverted to normal only after improvement in blood counts. She needs to be supported with antibiotics till then