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Microscopic Diagnosis Shows Uterine Cervix, Polypectomy, Small Cell Neuroendocrine Carcinoma. Explain
How would you interpret the following path report excerpt:
FINAL MICROSCOPIC DIAGNOSIS:
Uterine cervix, polypectomy A small cell neuroendocrine carcinoma.
Comment: Masses of mitotically active cells with very high N/C ratios,
nuclear molding, and positivity for AE1/AE3, chromogranin, and
synaptophysin comprise this polypoid mass. The tumor is CK20 negative.
Assuming that the patient has no primary tumor in the lung (which would be
very unlikely), the findings are those of small cell neuroendocrine
carcinoma, which is a rare but well—recognized type of cervical carcinoma
with a propensity to behave aggressively.
FINAL MICROSCOPIC DIAGNOSIS:
Uterine cervix, polypectomy A small cell neuroendocrine carcinoma.
Comment: Masses of mitotically active cells with very high N/C ratios,
nuclear molding, and positivity for AE1/AE3, chromogranin, and
synaptophysin comprise this polypoid mass. The tumor is CK20 negative.
Assuming that the patient has no primary tumor in the lung (which would be
very unlikely), the findings are those of small cell neuroendocrine
carcinoma, which is a rare but well—recognized type of cervical carcinoma
with a propensity to behave aggressively.
posted on
Mon, 10 Jun 2013
Medically reviewed by
Ask A Doctor - 24x7 Medical Review Team
Mon, 10 Jun 2013
Answered on
Mon, 10 Jun 2013
Last reviewed on
Hello, I would be happy to help you with your question.
I am very sorry about this finding. Basically, the results state that you have cancer of the uterus. The more detailed stains and comments have to do with classification of the 'cell type' from which the tumor originated. They are saying that the 'type' of cell found is rare in the uterus. They also comment that this is a type of cancer that behaves very 'aggressively'. This means that you need to have this treated as soon as possible. It is very important that you get in to see a GYNECOLOGIC ONCOLOGIST as soon as possible. If you are having trouble finding one, please contact me through the Premium service.
I hope that this helps. If you have more questions, please click on "ASK ME A QUESTION" link above to directly ask me a question
I am very sorry about this finding. Basically, the results state that you have cancer of the uterus. The more detailed stains and comments have to do with classification of the 'cell type' from which the tumor originated. They are saying that the 'type' of cell found is rare in the uterus. They also comment that this is a type of cancer that behaves very 'aggressively'. This means that you need to have this treated as soon as possible. It is very important that you get in to see a GYNECOLOGIC ONCOLOGIST as soon as possible. If you are having trouble finding one, please contact me through the Premium service.
I hope that this helps. If you have more questions, please click on "ASK ME A QUESTION" link above to directly ask me a question
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