Hi friend, Welcome to Health Care Magic Irrespective of any other finding, a positive TMT is an indication for angiography / It is the only way to directly ‘see’ the block, if any – and its location, extent, severity and so on. / CT angio is non-invasive study for the anatomy. If positive, you will need catheterisation, anyway. / Especially if one is symptomatic / Why was TMT done? / You need to be investigated to exclude Coronary Artery Disease. If you are not convinced... At times, there may be false positive or false negatives. The next step is TMT with thallium isotope. It is the ideal non-invasive way to evaluate ischemia / to assess the PHYSIOLOGY (function) – to see whether the blood arriving at the heart muscle. If there is a suggestion, the next step is to see the ANATOMY (structure) – undergo catheterisation and coronary angiography. Coronary arteriography is invasive but it is the gold standard for this. The aim of any investigation is to modify the treatment, based on the result. Intervention – dilatation with balloon and placing a stent (Angioplasty) - or CABG (Coronary Artery Bypass Graft) may be advised based on the results. Take care Wishing speedy recovery God bless Good luck