I am having edema in my legs to a point of pitting edema, it gets worse if i move or exercise. I have daily severe headaches that are getting more and more frequent and long, no OCT med helps. The headaches get worse with exercise ect ( I am an athlete, daily, I stopped once symptoms got too bad and every day). They are at the front and sides of my skull very close to the skin feeling verses in my skull. my face will look gaunt/drawn/deep dark eyes like someone sucked the water out of me ( I drink *plenty*) as well as my arms will get very vascular . Agitation with mood. There will be attacks where my body will just drop and i can feel the swelling in the lower and my face tighten up and my severe headache set in (coming with agitation). Dry skin/hair shedding too. My diet is healthy and well rounded, plenty of vegetables and lean meat ect. I have a clean health history. Dont drink/smoke/drugs. My liver,kidneys,adrenals, cortisol , pituitary ,and normal blood scans were normal. Did some base hormones with an endocrinologist , testosterone ect and they were normal too. Only abnormal thing was my b12 was 1595 ( I took *one* 5000mcg the day before but no active supplementation otherwise) The b12 helps. I had a headache for 12 hours that OCT wouldnt touch but taking 46mg iron made it go away. My HCT was 41 but I dont know if they did a smear and they did not test for iron. Everyone is baffled. Ive been so sick i can hardly function or get through work. I am not fatigued but I am weak ( for me) I am thinking that this is either an autoimmune or problem absorbing my b12/iron or heavy metals. I had a copper IUD for 3 years that was recently removed and my body improved (it HATED it, i was very bloated with constant discharge and pain despite the specialist OBGYM saying there was nothing wrong physically (did a special ultrasound) My joints are fine but my lymphs will get tender and/or swollen under my jaw on an off.