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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Should Zeffix Be Stopped And PCR Test Be Repeated?

I have been taken Zeffix for more than five year. Last PCR done in Germany show zero value with very small signals. I still take Zeffiex for more that 12 months after last metioned PCR. my wife also has Hepatitus b but she didn't take Zeffix. And we had sex this month.

My Question is I should stop zeffix. And do I need to repeat PCR after stopping several times.

Thanks

Thu, 18 Sep 2014
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Infectious Diseases Specialist,  's  Response
Hi,

Welcome to HCM.

I understand that uou have to repeat PCR frequently but it is necessary and it will indicate the viral load of hepatitis B which will denote your response to Zeffix.
Zeffix is an antiviral lamivudine which is quite effective for Hepatitis B.
If your spouse is also suffering from hepatitis B infection, she should also be treated as soon as possible as there are chances of her infecting you during intetcourse.
I suggest you get a PCR done now before stopping Zeffix, if vital load is 20,000 IU, then you do not need to repeat it.
I hope I have cleared your doubts.

Thanks.
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Should Zeffix Be Stopped And PCR Test Be Repeated?

Hi, Welcome to HCM. I understand that uou have to repeat PCR frequently but it is necessary and it will indicate the viral load of hepatitis B which will denote your response to Zeffix. Zeffix is an antiviral lamivudine which is quite effective for Hepatitis B. If your spouse is also suffering from hepatitis B infection, she should also be treated as soon as possible as there are chances of her infecting you during intetcourse. I suggest you get a PCR done now before stopping Zeffix, if vital load is 20,000 IU, then you do not need to repeat it. I hope I have cleared your doubts. Thanks.