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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Should Blood Work Showing Abnormal SGPT Level Indicate Cirrhosis Or Leukemia?

I went to the doctor with unexplained bruising all over my body, and unexplained itching all over my body. I had hep C 5 years ago that was treated with interferon and went through 6 months of heavy drinking from January to June of this year before going to rehab. He did blood work and it showed an ALT(SGPT) of 48 u/l with a ref range of <40, Bun/Creat 28 ratio with ref range of 10-24, gulcose of 109mg/dl with ref range of 74-106, rbc of 3.77 10#6/ul with a reference range of 4.2-5.40, a hematocrit of 35.3% with a ref range of 37-47%, and a MCH of 32.2 pg with a ref range of 27.0-32.0. What I want to know is should I be worried about Cirrhosis or Leukemia? If so, which one would be more probable? The doctor is doing more blood work, a liver ultra sound, and depending on the blood work, possibly a bone marrow test, but I am anxious to know something. My doctor is hesitant to give me an opinion without more facts but I just want to have an idea of what I am looking at. Can you please help me?
Mon, 1 Sep 2014
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Pathologist and Microbiologist 's  Response
Hello and welcome to HCM,
A history of bruising and itching all over the body and a raised SGPT levels suggests a liver disease.
Diseases of liver cause increase in bile salts which are responsible for itching and reduction in clotting factors which cause unexplained bruising.
The red blood cell count and hematocrit are slightly low.
The fasting glucose levels in also elevated.
The investigation given above suggests a liver disease rather than leukemia.
A liver biosy may be required.
Consult your doctor for further work up.


Thanks and take care
Dr Shailja P Wahal


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Should Blood Work Showing Abnormal SGPT Level Indicate Cirrhosis Or Leukemia?

Hello and welcome to HCM, A history of bruising and itching all over the body and a raised SGPT levels suggests a liver disease. Diseases of liver cause increase in bile salts which are responsible for itching and reduction in clotting factors which cause unexplained bruising. The red blood cell count and hematocrit are slightly low. The fasting glucose levels in also elevated. The investigation given above suggests a liver disease rather than leukemia. A liver biosy may be required. Consult your doctor for further work up. Thanks and take care Dr Shailja P Wahal