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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Should I Do Biopsy As I Have High Alk Phosphatase?

I had a hepatic function test that showed high alk phosphatase level it went from 150 to 170. I had also an ultrasound of my liver which shows no tumors. The doctor says I need a liver biopsy. I take several Aleve each plus lisinopril and omeprazole 20 mg twice daily. Should I have the biopsy?
Mon, 1 Sep 2014
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Internal Medicine Specialist,  's  Response
HI
Thanks for posting your query to Healthcaremagic .

There are many causes for raised alkaline phosphatase. Infact raised alkaline phosphatse can also be due to Bone or Intestinal problems apart from liver .

So going for a liver biopsy only for raised alkaline phosphatase is not advisable . If your raised alkaline phosphatase is associated with raised serum levels of gamma glutamyltransferase then the source of raised alkaline phosphatase is consider as liver .

Even in that case raised alkaline phosphatase could be due to frequent consumption of Aleve. I advise to stop taking Aleve and ask your docotr for a substitute . Also stop drinking alcohol .

Repeat the test after 1 month and revert back .

Any clarifications feel free to ask .
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Should I Do Biopsy As I Have High Alk Phosphatase?

HI Thanks for posting your query to Healthcaremagic . There are many causes for raised alkaline phosphatase. Infact raised alkaline phosphatse can also be due to Bone or Intestinal problems apart from liver . So going for a liver biopsy only for raised alkaline phosphatase is not advisable . If your raised alkaline phosphatase is associated with raised serum levels of gamma glutamyltransferase then the source of raised alkaline phosphatase is consider as liver . Even in that case raised alkaline phosphatase could be due to frequent consumption of Aleve. I advise to stop taking Aleve and ask your docotr for a substitute . Also stop drinking alcohol . Repeat the test after 1 month and revert back . Any clarifications feel free to ask .