Hi and thanks for the query, I would love to say that drugs generally used in migraine present different responses in different persons. It might be however necessary to try other existing options. In primary headaches like migraines, a careful followup to notice drug response and possible side effects might be required. A neurologists expertise could be necessary. This is because one might present with more than one primary headache signs or symptoms requiring a completely different combination of drugs. A careful examination shall be necessary to reconfirm the diagnosis, draw an appropriate management plan and monitor response. Thanks and hope this helps, Best regards, Luchuo, MD.