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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suffering From Hepatitis B Positive. Viral Quantification Test Done. Treatment?

sir i have been a hepatitis b positive for last one and half years.four months back i took viral quantification test.on that test i was having a viral copies of around 300 i.u/ml. last month i took test again inwhich i was having only 20 i.u /ml.will i become negative person /what are my chances.what kind of treatment i have to take?
Tue, 21 Aug 2012
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Internal Medicine Specialist 's  Response
your viral load is very low, that is good. You have chronic inactive hepatitis B (that is if you have normal liver enzymes as well). The guidelines state that there is no treatment necessary with such low viral load (anything <2000), if liver enzymes normal and no evidence of cirrhosis. However keep in mind that hepatitis B virus is carcinogenic, and increases your chances of liver cancer exponentially. I do know of some agressive liver doctors that treat Hepatitis B no matter what, and there are many treatment options. These include interferon (an injection given weekly, with A LOT of side effects), then Tenofovir or Entecavir (which are pills, it's taken once a day, minimal side effects). In your case with only 20 iu/ml, I would probably just watch you, as you might become negative in the future (chances are about 1-2% per year). You can't donate blood, and your sexual partner should be vaccinated against hepatitis B if he/she negative.
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Suffering From Hepatitis B Positive. Viral Quantification Test Done. Treatment?

your viral load is very low, that is good. You have chronic inactive hepatitis B (that is if you have normal liver enzymes as well). The guidelines state that there is no treatment necessary with such low viral load (anything 2000), if liver enzymes normal and no evidence of cirrhosis. However keep in mind that hepatitis B virus is carcinogenic, and increases your chances of liver cancer exponentially. I do know of some agressive liver doctors that treat Hepatitis B no matter what, and there are many treatment options. These include interferon (an injection given weekly, with A LOT of side effects), then Tenofovir or Entecavir (which are pills, it s taken once a day, minimal side effects). In your case with only 20 iu/ml, I would probably just watch you, as you might become negative in the future (chances are about 1-2% per year). You can t donate blood, and your sexual partner should be vaccinated against hepatitis B if he/she negative.