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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suffering From High SGOT, SGPT, Billirubin. Skin Irritation, Itching, Body Temperature Fluctuating. Reason? Taking Cetzine, Ursocol

Hello! I am 41 years old n am suffering from high levels of SGOT SGPT N BILLIRUBIN... Though this is not the first time.....I feel very sick my skin is very irritating n itchy n my body temp. Keeps fluctuating ...what cud be the reason? My gall bbladder was removed about 10 years ago! Right now I am taking Cetzine (Twice) for itch n Ursocol 300 thrice daily. I am on a strict diet of non greasy food with no spices...pl. advise why this keeps recurring time n again ..Also I wud like to mention that I had recently taken Primolute N to push my periods a little further... could this medicine have elevated the levels? If so pl. Advise as I will refrain from taking it in future! Thank You...:)
Sat, 14 Sep 2013
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General & Family Physician,  's  Response
Hello,
Thanks for the query to H.C.M. Forum.
As you mentioned that 10 years back you were operated for gallbladder removal.
Now S G O T , S G P T , serum blirubin level raised.
You mentioned that you are taking PRIMOLUT-N ( norethisterone) and after use of this drug your liver enzyme level raised.
So please note the side effects of primolut-n as,
cholestatic jaundice, urticaria ( as you are already taking cetrizine for allergy i.e.itching, so primolut-n further aggravate itching).
2nd thing primolut-n is contraindicated in hepatic dysfunction as all enzyme level are raised so this is not fit for you.
3rd special precaution should be taken in hepatic impairment during primolut - n use.
In my opinion please get in MRI and ultrasound of LIVER and consult a liver specialist .
In my opinion you should not take primolut-n .
Good luck.
Dr. het
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Suffering From High SGOT, SGPT, Billirubin. Skin Irritation, Itching, Body Temperature Fluctuating. Reason? Taking Cetzine, Ursocol

Hello, Thanks for the query to H.C.M. Forum. As you mentioned that 10 years back you were operated for gallbladder removal. Now S G O T , S G P T , serum blirubin level raised. You mentioned that you are taking PRIMOLUT-N ( norethisterone) and after use of this drug your liver enzyme level raised. So please note the side effects of primolut-n as, cholestatic jaundice, urticaria ( as you are already taking cetrizine for allergy i.e.itching, so primolut-n further aggravate itching). 2nd thing primolut-n is contraindicated in hepatic dysfunction as all enzyme level are raised so this is not fit for you. 3rd special precaution should be taken in hepatic impairment during primolut - n use. In my opinion please get in MRI and ultrasound of LIVER and consult a liver specialist . In my opinion you should not take primolut-n . Good luck. Dr. het