Hi welcome to HCM Dear , I can understand your concern for your wife s suffering from pains . The lower parts of your legs and your back take the brunt of your day-to-day life. You shouldn’t have to be in pain, though. For your info Any amount of medication will not help cure unless you remove the causes of sufferings . Lack of essential nutrients ,lack of activity lack of rest and care , dehydration , over exertion ,anxiety , constipation may be causing pains and restlessness . .Myoto can be used but not for long . It causes some side effects like breathlessness , abnormally low BP , headache , hypersensitivity . Before starting it you must inform your doctor. Including vitamin C & D in natural form as veges fruit , banana , lemon juice To get relief from pain and inflammation , ginger, garlic ,nuts turmeric powder in a cup of hot milk twice a day works as antibiotic and is a great antioxidant , Sunbath for vitamin D for strengthening immunity. Beside physio treatment make sure she is stretching of her legs ,sit ups , walk on heels and toes jogging on toes and for back - side bending backbending but not front bending is allowed. Massage with olive oil is also good for strengthening veins and muscles. and relieving pain . Hope this helps solve your query . Take care . All the best . .