Hi, Thanks for writing in. Pyelonephritis is the infection of the kidney and upper urinary pathway. This requires a longer course of antibiotics than usual. Partially treating pyelonephritis will cause the disease to not get eradicated and lead to antibiotic resistance. In the case of your mother it is suggested that she gets a urine culture and sensitivity test done. This will tell which antibiotics are required to eradicate the bacteria causing the pyelonephritis. The culture and sensitivity test will show which antibiotic will work the maximum and give relief in a short time. Having diabetes makes treatment difficult and this is probably the reason why she is taking longer to recover. If she does not like to eat then her diet is to be modified to include healthy food which can be given like fluids and juices. Hydration is important and she should be told to drink adequate fluids. Once the treatment of the infection is over then the urine culture should be done again to confirm that there is no persisting infection. If infection is still there then for few weeks specific urinary system antibiotics like nitrofurantoin can be started and monitored. Please do not worry.