Hi Dear !! Thanks for your query to HCM. Read and reviewed query. Based on facts of your query, You seem to suffer from- TB with DILI(Drug Induced Liver Injury) with ?Drug Induced Gastritis. This is mostly from accompanied Hepatitis, which could be controlled by your doctors-by change of medicines-like Rifampicin,pyrazinamide,INH. Just rule out of HIV and Hepatitis C , in which the deterioration is very common.So just rule out if your brother belongs to that group. High Protein, High Carbo, diet Plenty of fluids Directly observed DOT treatment. Immediate Replacement for Drug side effects. PPI-Like Pantoprazole in all / and with Domeperidone - in some may reduce the intolerance by vomitting. So Please Consult Senior Doctor incharge of the DOTS and he would take care of it accordingly. This Would go a long way for better happy life for you. Hope this would resolve your health issues early Welcome for any further query in this regard. Good Day !! Dr.Savaskar M.N. Senior Surgical Specialist and Thorasic / Chest Surgeon M.S.Genl-CVTS