Suggest Remedy For Depression When On Medication

I had a question but this is not about me this is for my girlfriend of a few years.. She has depression and has been taking anti depressions for quit sometime. Lately she is not even upset about what had caused her to go into the depression a few years ago. But up untill this point the doctors had kept upping her dosage for her anti depression medication. For the past few weeks she has felt worse. She doesn t want to talk a lot. She is not wanting to eat. She does not want to go out of the house and she has never been like this since we have been together.. I am just looking for an answer because I honestly do not know this much about it. I would much appreciate it if you could answer to the best of your ability... Thank you