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Suggest Remedy To Cure Syphilis
Hi , 28yrs Male 5.4ft, 50kgs .I had tested VDRL & TPHA , my VDRL results + & TPHA is negative , my RPR & VDRL ratio was 1:2, & I had took penicillin injection 1 month back too, & now I did my VDRL test again & its result is again positive.now RPR & VDRL ratio is 1:2,so please suggest me what should I do for got cure ????
posted on
Fri, 14 Mar 2014
Medically reviewed by
Ask A Doctor - 24x7 Medical Review Team
Thu, 3 Jul 2014
Answered on
Thu, 3 Jul 2014
Last reviewed on
Hi, Welcome to HCM.
VDRL and RPR positive whereas TPHA negative means that you are not having Syphilis at all. This is called as biological false positive. The reagents used in both VDRL and RPR are not derived from the causative agent of Syphilis. So it may be reactive in conditions other than Syphilis also, usually in low titre less than 8.In TPHA test, antigen is derived from the Syphilis causing organism, so this reactive serology is more confirmatory in case of diagnosis of Syphilis.
All penicillin were not useful in Syphilis. The exact type of penicillin in the correct dosage for correct duration is essential for Syphilis. Even with correct management, Syphilitic serology may take 6 months or more to become nonreactive. In your case, look for the cause of biological positive reaction and try to treat the same.
Consult a physician who is well-versed in the management of Syphilis and follow his advice.
DR S.Murugan
VDRL and RPR positive whereas TPHA negative means that you are not having Syphilis at all. This is called as biological false positive. The reagents used in both VDRL and RPR are not derived from the causative agent of Syphilis. So it may be reactive in conditions other than Syphilis also, usually in low titre less than 8.In TPHA test, antigen is derived from the Syphilis causing organism, so this reactive serology is more confirmatory in case of diagnosis of Syphilis.
All penicillin were not useful in Syphilis. The exact type of penicillin in the correct dosage for correct duration is essential for Syphilis. Even with correct management, Syphilitic serology may take 6 months or more to become nonreactive. In your case, look for the cause of biological positive reaction and try to treat the same.
Consult a physician who is well-versed in the management of Syphilis and follow his advice.
DR S.Murugan
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